To provoke, particularly if in a return jest
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A man pushes the other and the victim returns, "What's your problem," in anger.

Submitted on July 07, 2010

Additional definitions for 'what's wrong with you':

what's wrong with youMocking sense, making light of ones ailment
what's wrong with youInsulting sense, to imply if something serious is wrong out of spite or to outright say -- Are you stupid?
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